Patent · US Active

Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors

US7998507B2 · kind B2 · utility

2Cited by

83References

35Claims

0Family size

Assignee

Elan Pharma International Ltd. · IE

Inventors

H. William Bosch · Via Enrico Fermi, US
Greta G. Cary · Lansdale, US
Douglas Hovey · Gilbertsville, US
Rajeev Jain · Framingham, US
Laura Kline · Harleysville, US
Elaine Merisko-Liversidge · West Chester, US
Kevin Ostrander · Reading, US
Niels P. Ryde · Malvern, US
Stephen B. Ruddy · Schwenksville, US

Key dates

Filing date	Dec 7, 2005
Grant date	Aug 16, 2011
Priority date	—
Expiry date	Nov 9, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/66
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nanoparticulate compositions comprising at least one poorly soluble MAP kinase inhibitor and at least one surface stabilizer are described. The nanoparticulate compositions have an average particle size of less than about 2000 nm. The invention also describes methods of making and using such compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.