Aptamers to von Willebrand factor and their use as thrombotic disease therapeutics
US7998940B2 · kind B2 · utility
3Cited by
125References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2009 |
| Grant date | Aug 16, 2011 |
| Priority date | — |
| Expiry date | Aug 18, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/321
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates generally to the field of nucleic acids and more particularly to aptamers capable of binding to von Willebrand Factor useful as therapeutics in and diagnostics of thrombotic diseases and/or other diseases or disorders in which von Willebrand Factor mediated platelet aggregation has been implicated. The invention further relates to materials and methods for the administration of aptamers capable of binding to von Willebrand Factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.