Inhibitors of AKT (protein kinase B)

US7998977B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Sajan Joseph · Indianapolis, US
• Renhua Li · Wilmington, US
• Michael R. Myers · Fishers, US
• Aktham Aburub · Carmel, US
• Jenny Pingqi Dai · Hershey, US
• Christopher Randall Schmid · Indianapolis, US

Key dates

• Filing date: Jun 12, 2007
• Grant date: Aug 16, 2011
• Expiry date: Jul 28, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

4-[5-(2-Amino-ethanesulfonyl)-isoquinolin-7-yl]-phenol or a pharmaceutically acceptable salt thereof or a hydrate of the compound or the salt thereof as Akt inhibitors that are antineoplastic and/or antiviral agents as well as compositions comprising these compounds and methods of using these compounds.