LXR and FXR modulators
US7998995B2 · kind B2 · utility
26Cited by
11References
45Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2007 |
| Grant date | Aug 16, 2011 |
| Priority date | — |
| Expiry date | Dec 7, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the invention are disclosed, such as compounds of formulae LX-LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.