Patent · US Active

2′-silyl containing thiocarbonate protecting groups for RNA synthesis

US7999087B2 · kind B2 · utility

107Cited by

7References

22Claims

0Family size

Assignee

AGILENT TECHNOLOGIES, INC. · US

Inventors

Douglas J. Dellinger · Boulder, US
Agnieska Sierzchala · Boulder, US
Marvin H. Caruthers · Boulder, US
Geraldine F. Dellinger · Boulder, US

Key dates

Filing date	Nov 15, 2007
Grant date	Aug 16, 2011
Priority date	—
Expiry date	Jan 29, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Nucleoside monomers, nucleic acids, e.g., oligonucleotides and polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein. Aspects of the invention include 2′ silyl containing thiocarbonate protecting groups. Corresponding compositions and methods are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.