Patent · US Active

Anti-myosin Va siRNA and skin depigmentation

US7999096B2 · kind B2 · utility

1Cited by

0References

14Claims

0Family size

Assignee

PIERRE FABRE DERMO-COSMETIQUE · FR

Inventors

Anne-Marie Schmitt-Milas · Tournefeuille, FR
Jo Lambert · Zevergem, BE
Wendy Westbroek · Rockville, US
Mireille Van Gele · Adegem, BE

Key dates

Filing date	Dec 12, 2006
Grant date	Aug 16, 2011
Priority date	—
Expiry date	Feb 28, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/3231
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to novel isolated siRNAs comprising a sense RNA strand and a complementary antisense RNA strand which together form an RNA duplex, characterized in that the sense RNA strand comprises a sequence which has at most one nucleotide that is distinct in relation to a fragment of 14 to 30 contiguous nucleotides of the nucleotide sequence of exon F of the gene encoding the myosin Va protein, and also to compositions comprising at least one such siRNA, and to the use of at least one such siRNA as a cosmetic or therapeutic agent for skin depigmentation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.