Methods for fat quantification with correction for noise bias
US8000769B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 24, 2007 |
| Grant date | Aug 16, 2011 |
| Priority date | — |
| Expiry date | Oct 10, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/4828
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are disclosed for calculating a fat fraction corrected for noise bias of one or more voxels of interest using a magnetic resonance imaging (MRI) system. A plurality of image data sets are obtained each corresponding to NMR k-space data acquired using a pulse sequence with an individual associated echo time tn. A system of linear equations is formed relating image signal values to a desired decomposed calculated data vector having a component such as a water and fat combination having zero mean noise, or having a real fat component and a real water component. A fat fraction is calculated from at least one component of the decomposed calculated data vector. In another embodiment, the system of linear equations is normalized and can directly estimate a fat fraction or a water fraction having reduced noise bias.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.