Targeted MR imaging agents
US8003078B2 · kind B2 · utility
1Cited by
4References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 29, 2007 |
| Grant date | Aug 23, 2011 |
| Priority date | — |
| Expiry date | Jul 24, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D257/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
MRI contrast agents that employ paramagnetic agents and chemical exchange saturation transfer (paraCEST) and which are coupled to targeted particulate delivery vehicles provide sufficient concentration of the paraCEST contrast agents to obtain useful images of target tissues or organs. In addition, the image contrast may be switched on or off with a presaturation radio frequency pulse, avoiding the necessity obtaining pre-injection and post-injection images.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.