Nanoparticulate corticosteroid and antihistamine formulations methods of making, and methods of administering thereof

US8003127B2 · kind B2 · utility

Assignee

• Elan Pharma International Ltd. · IE

Inventors

• Gary Liversidge · West Chester, US
• Scott Jenkins · San Francisco, US
• H. William Bosch · Via Enrico Fermi, US
• Christian F. Wertz · St. Louis Park, US

Key dates

• Filing date: Mar 23, 2006
• Grant date: Aug 23, 2011
• Expiry date: May 19, 2029

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/904
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions comprising a nanoparticulate corticosteroid and an antihistamine are described. The compositions are useful in the prophylaxis and chronic treatment of asthma in adults and pediatric patients and for the relief of allergic conjunctivitis, symptoms of seasonal allergic rhinitis in adults and pediatric patients. Combining an antihistamine with a nanoparticulate corticosteroid in a single formulation results in improved efficacy.