Methods of screening for risk of proliferative disease and methods for the treatment of proliferative disease
US8003327B2 · kind B2 · utility
1Cited by
33References
8Claims
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Key dates
| Filing date | Jan 22, 2009 |
| Grant date | Aug 23, 2011 |
| Priority date | — |
| Expiry date | Jul 24, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.