Substituted prolinamides, the preparation thereof and the use thereof as pharmaceutical compositions

US8003639B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Henning Priepke · Warthausen, DE
• Georg Dahmann · Biberach an der Riß, DE
• Kai Gerlach · Biberach, DE
• Herbert Nar · Ochsenhausen, DE
• Roland Pfau · Biberach, DE
• Annette Schuler-Metz · Ulm, DE
• Wolfgang Wienen · Äpfingen, DE

Key dates

• Filing date: Feb 13, 2007
• Grant date: Aug 23, 2011
• Expiry date: May 4, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides new substituted prolinamides of the general formula (I) in which D, L, E, G, J, M, R3, R4, R5, and R13 are defined as in claim 1, their tautomers, their enantiomers, their diastereomers, their mixtures and their salts, more particularly their physiologically tolerated salts with organic or inorganic acids or bases, which exhibit valuable properties.