Heterocyclic substituted bisarylurea derivatives

US8003657B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Frank Stieber · Heidelberg, DE
• Alfred Jonczyk · Darmstadt, DE
• Guenter Hoelzemann · Seeheim-Jugenheim, DE
• Hans-Peter Buchstaller · Griesheim, DE
• Lars Burgdorf · Frankfurt am Main, DE
• Wilfried Rautenberg · Reinheim, DE
• Hartmut Greiner · Darmstadt, DE

Key dates

• Filing date: Oct 6, 2005
• Grant date: Aug 23, 2011
• Expiry date: Sep 29, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to heterocyclic substituted bisarylurea derivatives of formula I, the use of the compounds of formula I as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient.