Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors
US8003663B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jul 31, 2007 |
| Grant date | Aug 23, 2011 |
| Priority date | — |
| Expiry date | Nov 15, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo [3,4-b]pyridin-5-yl]methyl}-4-({8-[(2-hydroxyethyl) (methyl)amino]octanoyl}amino)benzamide, whose formula isor a salt thereof, such as the monohydrochloride salt thereof.The invention also provides the use of the compound or salt as inhibitors of phosphodiesterase type IV (PDE4) and/or for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, or rhinitis (e.g. allergic and/or non-allergic rhinitis).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.