Topical nanoparticulate spironolactone formulation
US8003690B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 13, 2002 |
| Grant date | Aug 23, 2011 |
| Priority date | — |
| Expiry date | Feb 11, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P17/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a topical nanoparticulate spironolactone formulation comprising nanoparticles having a mean diameter, measured by a photon correlation spectroscopy, in the range of from about 300 nm to about 900 nm. The nanoparticles are incorporated into a crystalline network system comprising a dispersion of solid crystals of polar lipids, said lipids exposing their hydrophilic side outwards and their hydrophobic side inwards towards the spironolactone nanoparticles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.