Patent · US Active

Receptor-based interaction trap

US8003757B2 · kind B2 · utility

3Cited by

16References

5Claims

0Family size

Assignee

VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW · BE

Inventors

Sven Eyckerman · Nazareth, BE
Xaveer Van Ostade · Ekeren, BE
Joel Vandekerckhove · Loppem, BE
Annick Verhee · Lichtervelde, BE
Jan Tavernier · Balegem, BE

Key dates

Filing date	Dec 14, 2009
Grant date	Aug 23, 2011
Priority date	—
Expiry date	Dec 14, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2799/06
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Described is a recombinant receptor comprising an extracellular ligand-binding domain and a cytoplasmic domain that comprises a heterologous bait polypeptide. The recombinant receptor is activated by binding of a ligand to the ligand-binding domain and by binding of a prey polypeptide to the heterologous bait peptide. The invention also discloses a method for detecting compound-compound binding using the recombinant receptor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.