Sulphoximine-substituted quinoline and quinazoline derivatives as kinase inhibitors

US8003787B2 · kind B2 · utility

Assignee

• Bayer Schering Pharma AG · DE

Inventors

• Knut Eis · Berlin, DE
• Olaf Prien · Berlin, DE
• Ulrich Lücking · Berlin, DE
• Judith Günther · Berlin, DE
• Dieter Zopf · Marburg, DE
• Dirk Brohm · Mettmann, DE
• Verena Vöhringer · Wuppertal, DE
• Elisabeth Woltering · Hilden, DE
• Hartmut Beck · Wuppertal, DE
• Mario Lobell · Wuppertal, DE
• Volkhart Min-Jian Li · Velbert, DE
• Susanne Greschat · Goldkronach, DE

Key dates

• Filing date: May 23, 2008
• Grant date: Aug 23, 2011
• Expiry date: May 23, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a quinoline or quinazoline derivative having the general formula (A):in which R3, R4, W, Y and Q are indicated in the description and the claims, the use of the compounds of the general formula (A) for the treatment of various disorders, and the preparation of compounds of the general formula (A).