Thiophene derivatives as S1P1/EDG1 receptor agonists
US8003800B2 · kind B2 · utility
12Cited by
4References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 10, 2007 |
| Grant date | Aug 23, 2011 |
| Priority date | — |
| Expiry date | Jan 15, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH═CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.