Synthetic method and automation device for fluorine-18-ACETATE
US8007730B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 5, 2009 |
| Grant date | Aug 30, 2011 |
| Priority date | — |
| Expiry date | Mar 3, 2030 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J19/004
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
An automatic synthesis device for fluorine-18-ACETATE ([18F]fluoroacetate) consists of a machinery housing that has multiple reactors and multiple raw material containers, and uses multiple control valves between each reactor and container, and operates the control valves through a control system to charge the raw material from each container to each reactor in an automatic and sequential fashion to execute the six procedures: fluorination, azeotropic dewatering, synthesis (reaction with precursors), purification and separation, hydrolysis and neutralization, purification and collection. The operation simply requires adding raw materials to the containers in advance, turning on power, charging reactive gases. In 50 minutes, the process to produce the product will be completed. The operation is really simple and can effectively improve production efficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.