Method for ProNGF assay for in vitro diagnosis of cancer in particular breast, thyroid or lung cancer and therapeutic use of ProNGF
US8008009B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jan 30, 2007 |
| Grant date | Aug 30, 2011 |
| Priority date | — |
| Expiry date | Feb 14, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns a method for in vitro diagnosis of cancer, in particular breast, thyroid or lung cancer, which consists in determining the presence of ProNGF in a biological sample derived from a patient suspected of suffering from cancer, in particular breast, thyroid or lung cancer. Said method may be used for early diagnosis, screening, therapeutic follow-up, prognosis and for diagnosing relapses in cancer and in particular breast, thyroid or lung cancer.The present invention also concerns the use of a ProNGF inhibitor for preparing a drug, said drug being in particular useful for blocking remote dissemination and cell invasion in patients suffering from cancer, in particular breast, thyroid or lung cancer.The invention is applicable in the field of diagnosis and therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.