Patent · US Active

Natural ligand of G protein coupled receptor RCC356 and uses thereof

US8008023B2 · kind B2 · utility

2Cited by

0References

11Claims

0Family size

Assignee

CHEMCOM S.A. · BE

Inventors

Frédéric Sallman · Vilvoorde, BE
Alex Veithen · Genappe, BE
Magali Philippeau · Wemmel, BE

Key dates

Filing date	May 12, 2008
Grant date	Aug 30, 2011
Priority date	—
Expiry date	Aug 29, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/02
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to the identification of isovaleric acid as a natural ligand of the RCC356 G-protein coupled receptor (GPCR). The invention encompasses the use of the interaction of RCC356 polypeptides and isovaleric acid as the basis of screening assays for agents that modulate the activity of the RCC356 receptor. The invention also encompasses diagnostic and other assays performed based upon the RCC356/isovaleric acid interaction, as well as kits for performing diagnostic and screening assays.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.