Patent · US Active

Photochemical internalization for delivery of molecules into the cytosol

US8008077B2 · kind B2 · utility

1Cited by

5References

24Claims

0Family size

Assignee

PCI BIOTECH AS · NO

Inventors

Kristian Berg · Heggedal, NO
Lina Prasmickaite · Oslo, NO
Anders Hogset · Oslo, NO
Pal Kristian Selbo · Oslo, NO

Key dates

Filing date	May 9, 2007
Grant date	Aug 30, 2011
Priority date	—
Expiry date	May 9, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/5156
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a method for introducing a molecule into the cytosol of a cell in which the cell is contacted with a photosensitising agent, the cell is irradiated with light of a wavelength effective to activate the photosensitising agent and, substantially at the same time or after the irradiation, the cell is contacted with the molecule to be introduced, particularly for use in cancer treatment, gene therapy and vaccination.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.