Patent · US Active

Macrocyclic compounds and compositions useful as BACE inhibitors

US8008250B2 · kind B2 · utility

0Cited by

1References

8Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Andreas Lerchner · Binningen, CH
Rainer Machauer · Glückstadt, DE
Marina Tintelnot-Blomley · Maulburg, DE
Oliver Simic · Basel, CH

Key dates

Filing date	Jan 13, 2006
Grant date	Aug 30, 2011
Priority date	—
Expiry date	Nov 2, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D419/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Macrocyclic compounds of the formula in which R1, R3, V1, V2, X1, X2, Y, Z, Ar, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17 or 18, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them are presented.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.