Patent · US Active

Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

US8008456B2 · kind B2 · utility

19Cited by
18References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 7, 2007
Grant dateAug 30, 2011
Priority date
Expiry dateOct 6, 2029

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Non-natural amino acids and polypeptides with non-natural amino acids are disclosed. Further, polypeptides with non-natural amino acids that are subject to post-translational modification are disclosed. Additionally, methods of making, purifying, and using non-natural amino acids and polypeptides with non-natural amino acids are disclosed. The non-natural amino acids, by themselves or as part of a polypeptide, can include a wide range of possible functionalities, but typically have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Uses for the non-natural amino acids and polypeptides with non-natural amino acids include diagnostic, therapeutic, and various biotechnology uses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.