Promoter for introducing a gene into a lymphocyte or blood cell and application thereof
US8008467B2 · kind B2 · utility
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1References
18Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 5, 2006 |
| Grant date | Aug 30, 2011 |
| Priority date | — |
| Expiry date | Jul 14, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.