Topical gel formulation comprising organophosphate insecticide and preparation thereof
US8012498B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Jul 12, 2005 |
| Grant date | Sep 6, 2011 |
| Priority date | — |
| Expiry date | Mar 17, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/14
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a topical gel pharmaceutical formulation of insecticide suitable for treating an ectoparasite in a mammal, comprising: a) about 0.1-10% by weight of an insecticide; b) at least about 75% by weight of an organic solvent selected from the group consisting of a lower alkyl alcohol, a ketone, a glycol and a mixture thereof, wherein the organic solvent contains at least about 40% by weight of the lower alkyl alcohol; and c) at least one polymer selected from the group consisting of a cellulosic polymer, acrylates, methacrylates, and polyvinyl pyrrolidone. The present gel pharmaceutical formulation preferably contains malathion and optionally contains isopropyl myristate. The present invention further provides a process of preparing as well as a method of treating ectoparasites in a mammal using the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.