Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
US8012704B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jul 6, 2010 |
| Grant date | Sep 6, 2011 |
| Priority date | — |
| Expiry date | Jul 6, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/495
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the molecule referred to as ALK-1, and its role as a type I receptor for members of the TGF-β family. The molecule has a role in the phosphorylation of Smad-5 and Smad1, which also act as activators of certain genes. Aspects of the invention relate to this interaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.