Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US8012937B2 · kind B2 · utility
10Cited by
3References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 22, 2006 |
| Grant date | Sep 6, 2011 |
| Priority date | — |
| Expiry date | Jun 30, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/47
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel gene 098P4B6 (also designated STEAP-2) and its encoded protein, and variants thereof, are described wherein 98P4B6 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 98P4B6 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 98P4B6 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 98P4B6 can be used in active or passive immunization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.