Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors
US8012966B2 · kind B2 · utility
25Cited by
2References
8Claims
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Assignee
Inventors
Key dates
| Filing date | Jan 24, 2007 |
| Grant date | Sep 6, 2011 |
| Priority date | — |
| Expiry date | May 23, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8X, Y and have the meaning cited in the specification. Also disclosed are the pharmaceutical compositions containing the foregoing compounds, methods for the preparation and pharmaceutical use thereof, particularly as protein kinase inhibitors. Formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.