Antitumoral analogs of ET-743
US8012975B2 · kind B2 · utility
6Cited by
29References
74Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 22, 2006 |
| Grant date | Sep 6, 2011 |
| Priority date | — |
| Expiry date | Dec 22, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D497/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antitumor compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.