Raman difference spectra based disease classification
US8013991B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 8, 2008 |
| Grant date | Sep 6, 2011 |
| Priority date | — |
| Expiry date | Aug 5, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V20/69
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A method to diagnosis a disease state of an unknown sample. A test Raman data set for an unknown sample is generated. A reference Raman database is provided where the database contains a plurality of reference Raman data sets and a plurality of reference Raman difference data sets. The reference Raman difference data set is generated by determining a difference between a first reference Raman data set and a second reference Raman data set. A first reference Raman data set is associated with first known sample and associated with one or more of: a first known disease state and a first known clinical outcome. A second reference Raman data set is associated with a second known sample and associated with one or more of: a second known disease state and a second known clinical outcome. A diagnosis is provided of whether the unknown sample has a first disease state or a second disease state by comparing the test Raman dataset to said plurality of reference Raman difference data sets in the reference Raman database using a chemometric technique.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.