Patent · US Active

Glimepiride- and insulin-induced glycosylphosphatidylinositol-specific phospholipase C regulation

US8017350B2 · kind B2 · utility

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0References

11Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Guenter Mueller · Pocking, DE
Wendelin Frick · Bad Camberg, DE
Rudolf Schneider · Niedernhausen, DE

Key dates

Filing date	Aug 14, 2006
Grant date	Sep 13, 2011
Priority date	—
Expiry date	Nov 2, 2026

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/566
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to a method for identification of a chemical compound which modulates the activity of mammalian GPI-PLC whereina] a mammalian cell is incubated with glimepiride;b] hcDIGs of the cells of a] are prepared;c] the hcDIGs from b] are incubated with a chemical compound;d] the activity of the GPI-PLC from the hcDIGs of c] is determined.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.