Patent · US Active

Method for transformation using mutant acetolactate synthase gene

US8017400B2 · kind B2 · utility

14Cited by
2References
6Claims
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Key dates

Filing dateMay 9, 2006
Grant dateSep 13, 2011
Priority date
Expiry dateMar 23, 2028

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/8274
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Transformed cells are efficiently selected using a mutant ALS gene having high specificity to PC herbicides. The transformation method comprises the steps of: transforming a host cell with a recombination vector containing a gene of interest and a gene coding for a mutant acetolactate synthase having mutation of glycine corresponds to position 95 of the amino acid sequence of a wild-type acetolactate synthase derived from rice to alanine; culturing the transformed cell obtained in the former step in the presence of a pyrimidinyl carboxy herbicide; and wherein the gene coding for the mutant acetolactate synthase is used as a selection marker.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.