Patent · US Active

Metal-binding compounds and uses therefor

US8017728B2 · kind B2 · utility

5Cited by
145References
31Claims
0Family size

Inventors

Key dates

Filing dateNov 2, 2009
Grant dateSep 13, 2011
Priority date
Expiry dateNov 2, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2800/522
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides a method of reducing the damage done by reactive oxygen species (ROS) in an animal. The invention also provides a method of reducing the concentration of a metal in an animal. These methods comprise administering to the animal an effective amount of a metal-binding compound as further described in the application. The invention further provides a method of reducing the damage done by ROS to a cell, a tissue or an organ that has been removed from an animal. This method comprising contacting the cell, tissue or organ with a solution or medium containing an effective amount of a metal-binding compound of the invention. The invention further provides novel metal-binding compounds, pharmaceutical compositions comprising the metal-binding compounds, and kits comprising a container holding a metal-binding compound of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.