T cell receptors which specifically bind to VYGFVRACL-HLA-A24
US8017730B2 · kind B2 · utility
2Cited by
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1Claims
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Assignee
Inventors
Key dates
| Filing date | May 19, 2006 |
| Grant date | Sep 13, 2011 |
| Priority date | — |
| Expiry date | Feb 12, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides isolated T cell receptors (TCRs) having the property of specifically binding to the VYGFVRACL (SEQ ID NO:1)-HLA-A24 peptide-MHC. Such TCRs are useful, either alone or associated with a therapeutic agent, for targeting cancerous cells presenting the complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.