Tumor marker for pancreatic cancer
US8017732B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Jul 24, 2008 |
| Grant date | Sep 13, 2011 |
| Priority date | — |
| Expiry date | Aug 8, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/75
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel protein and a fragment thereof useful as a tumor marker of pancreatic cancer are disclosed. This protein or a fragment thereof is a modified α-fibrinogen protein containing an oxidized amino acid residue(s) or a fragment thereof containing said oxidized amino acid residue(s). The oxidized amino acid residue(s) is one or more amino acid residues selected from the group consisting of (a) a proline residue corresponding to the proline residue at the position of 530 in SEQ ID NO: 2, and (b) a proline residue corresponding to the proline residue at the position of 565 in SEQ ID NO: 2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.