Patent · US Active

Method for increasing plasma volume by administering a plasma expander comprising basic alpha keratose

US8021830B2 · kind B2 · utility

7Cited by
24References
14Claims
0Family size

Assignee

Inventor

Key dates

Filing dateSep 12, 2008
Grant dateSep 20, 2011
Priority date
Expiry dateApr 10, 2030

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P7/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A liquid plasma expander or resuscitation fluid composition for use in a subject in need thereof, comprising, consisting of; or consisting essentially of: (a) a keratin derivative (preferably alpha keratose, gamma keratose, or combinations thereof, and with basic alpha keratose preferred over acidic alpha keratose); and (b) an electrolyte solution, with the keratin derivative solubilized in the electrolyte solution to form a homogeneous liquid composition. Blood substitutes formed therefrom and methods of making and using the same are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.