Rapid and sensitive detection of cells and viruses
US8021848B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Sep 6, 2002 |
| Grant date | Sep 20, 2011 |
| Priority date | — |
| Expiry date | May 17, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/33
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides efficient methods for rapidly and sensitively identifying cellular and viral targets in medical, industrial, and environmental samples. The invention labels targets and then detects them using large area imaging. Diagnostic tests based on the invention can be rapid, ultrasensitive, quantitative, multiplexed, and automated. The tests minimize sample preparation and do not require nucleic acid amplification or cell culture. A broad range of cells and viruses can be detected by the tests. Tests based on the invention can deliver the high level sensitivity of nucleic acid amplification tests, the user-friendliness, and speed of immunoassays, as well as the cost effectiveness and quantification offered by microbiological tests. The invention embodies the best attributes of the current diagnostic technologies, while addressing gaps in the diagnostic repertoire.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.