Phenylpentadienoyl derivatives and their use as PAR 1 antagonists
US8022064B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 19, 2007 |
| Grant date | Sep 20, 2011 |
| Priority date | — |
| Expiry date | Sep 30, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/112
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of general formula (I): wherein: R1 and R2, identical or different, represent: an atom of hydrogen or halogen, CN or NO2, with R1 and R2 not representing hydrogen simultaneously, m represents: 1 or 2 n represents: 0, 1 or 2 R3 represents: phenyl substituted or not by one or more residues chosen among halogen, hydroxyl or C1-C6 alkyl; C2-C6 alkyl substituted or not by one or more residues chosen among halogen or hydroxyl; cycloalkyl; pyridine; thiophene; pyrrole substituted or not by C1-C6 alkyl; thiazole or furan; or the therapeutically-acceptable salts or solvates thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.