Patent · US Active

Method for preventing and treating Alzheimer's disease

US8022180B2 · kind B2 · utility

3Cited by

3References

14Claims

0Family size

Assignee

Affiris Forschungs-und Entwicklungs GmbH · AT

Inventors

Frank Mattner · Wien, AT
Walter Schmidt · Wien, AT

Key dates

Filing date	Jul 6, 2005
Grant date	Sep 20, 2011
Priority date	—
Expiry date	Oct 2, 2027

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/2821
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the use of a compound comprising the following amino acid sequence X1X2X3X4X5X6X7, wherein X1 is an amino acid, except of C, X2 is an amino acid, except of C, X3 is an amino acid, except of C, X4 is an amino acid, except of C, X5 is an amino acid, except of C, X6 is not present or any amino acid, X7 is not present or any amino acid, and wherein X1X2X3X4X5X6 is not DAEFRH, said compound having a binding capacity to an antibody being specific for the natural N-terminal Aβ42 sequence DAEFRH, and 5-mers thereof having a binding capacity to said antibody being specific for the natural N-terminal Aβ42 sequence DAEFRH, for the preparation of a vaccine for Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.