Pyrimidine derivatives as PI3K inhibitor and use thereof
US8022205B2 · kind B2 · utility
6Cited by
3References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 7, 2007 |
| Grant date | Sep 20, 2011 |
| Priority date | — |
| Expiry date | Jul 7, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A drug is provided that is useful as a preventive or therapeutic for cancer as a result of having superior PI3K inhibitory effects as well as superior stability in the body and water-solubility.A compound, or pharmaceutically acceptable salt thereof, represented by formula (I):[wherein, X represents a single bond, etc.; Y represents a single bond, etc. (provided that X and Y are not simultaneously single bonds); Z represents a hydrogen atom, etc.; m represents an integer of 1 or 2; and R1 represents a cyclic substituent].
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.