Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use
US8022235B2 · kind B2 · utility
8Cited by
8References
14Claims
0Family size
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Key dates
| Filing date | May 30, 2008 |
| Grant date | Sep 20, 2011 |
| Priority date | — |
| Expiry date | Aug 16, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/094
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.