Patent · US Active

Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma

US8025803B2 · kind B2 · utility

0Cited by

6References

8Claims

0Family size

Assignee

LFB Biotechnologies · FR

Inventors

Francoise Bridey · Lons-le-Saunier, FR
Roland Schmitthaeusler · Montigny-le-Bretonneux, FR

Key dates

Filing date	Jul 7, 2008
Grant date	Sep 27, 2011
Priority date	—
Expiry date	Jul 7, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N9/6489
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

An ion-exchange chromatography support for reducing the ADAMTS13 amount present in a plasma-derived solution containing human von Willebrand factor. The support includes a large-pore, vinyl polymer-type resin bearing DEAE groups, and a buffer including trisodium citrate, sodium chloride, calcium chloride, glycine and lysine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.