Methods for rapid identification and quantitation of nucleic acid variants
US8026084B2 · kind B2 · utility
25Cited by
227References
34Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 21, 2006 |
| Grant date | Sep 27, 2011 |
| Priority date | — |
| Expiry date | Aug 15, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.