Peptide tyrosinase inhibitors and uses thereof
US8026208B2 · kind B2 · utility
1Cited by
28References
37Claims
0Family size
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Inventor
Key dates
| Filing date | Jun 25, 2008 |
| Grant date | Sep 27, 2011 |
| Priority date | — |
| Expiry date | Aug 12, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are peptides, which inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. The peptides are characterized by sequences RADSRADC (SEQ ID NO: 2) and PLG-OH. Methods of skin treatment are also provided, the methods further including use of a peptide characterized by the amino acid sequence SFLLRN (SEQ ID NO: 1).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.