Method for determining an analyte in a sample
US8027040B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 24, 2008 |
| Grant date | Sep 27, 2011 |
| Priority date | — |
| Expiry date | Oct 13, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/258
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
In one aspect of the invention, a method or apparatus is described for determining concentration(s) of one or more analytes in a sample using plasmonic excitations. In another aspect, a method relates to designing systems for such concentration determination, wherein metallic nanostructures are used in combination with local electrical detection of such plasmon resonances via a semiconducting photodetector. In certain aspects, the method exploits the coupling of said metallic nanostructure(s) to a semiconducting photodetector, said detector being placed in the “metallic structure's” near field. Surface plasmon excitation can be transduced efficiently into an electrical signal through absorption of light that is evanescently coupled or scattered in a semiconductor volume. This local detection technique allows the construction of sensitive nanoscale bioprobes and arrays thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.