Processing method for the long-term stabilization of biological red blood cell volume
US8029978B2 · kind B2 · utility
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12References
21Claims
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Key dates
| Filing date | Dec 30, 2005 |
| Grant date | Oct 4, 2011 |
| Priority date | — |
| Expiry date | Apr 4, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/2525
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a processing method for long-term stabilization of biological red blood cell volume. The red blood cells can be further used in reference materials and calibrators of a hematology analyzer. The method of the present invention comprises contacting the sample with a solution comprising a membrane-fixation reagent and an aldehyde for a processing period to terminate or slow down the red blood cell metabolism. It is provided by experiments that such process enables the volume of the red blood cells to be stable in a period over 120 days.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.