Microfabricated apparatus for cell based assays
US8030062B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 23, 2008 |
| Grant date | Oct 4, 2011 |
| Priority date | — |
| Expiry date | Jan 22, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0688
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Apparatus and methods are provided for performing cell growth and cell based assays in a liquid medium. The apparatus comprises a base plate supporting a plurality of micro-channel elements, each micro-channel element comprising a cell growth chamber, an inlet channel and an outlet channel, a cover plate positioned over the base plate to define the chambers and connecting channels. Means are incorporated in the cell growth chambers, for cell attachment and cell growth. In particular, the invention provides a rotatable disc microfabricated for performing cell growth and cell based assays. The apparatus and method can be used for the growth of cells and the detection and measurement of variety of biochemical processes and products using non-invasive techniques, that is techniques which do not compromise the integrity or viability of cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.