Patent · US Active

Spirocompounds useful as modulators for dopamine D3 receptors

US8030322B2 · kind B2 · utility

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5Claims
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Assignee

Inventors

Key dates

Filing dateApr 24, 2007
Grant dateOct 4, 2011
Priority date
Expiry dateAug 25, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula (I) or salts thereofwherein A, X, R2, R4 and n are defined herein, processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3 receptors, e.g., to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, premature ejaculation or to enhance cognition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.