Process for the preparation of an amine

US8034978B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Jan Eberhardt · Mannheim, DE
• Harald Meiβner · Nümbrecht, DE
• Bram Willem Hoffer · Heidelberg, DE
• Johann-Peter Melder · Schifferstadt, DE
• Ekkehard Schwab · Neustadt, DE

Key dates

• Filing date: May 24, 2007
• Grant date: Oct 11, 2011
• Expiry date: Jan 22, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for preparing an amine by reacting an aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group consisting of primary and secondary amines in the presence of a heterogeneous catalyst, wherein the reaction is carried out using a suspended catalyst as heterogeneous catalyst and is carried out in the semibatch mode in which the nitrogen compound as one reactant is placed in the reaction vessel and the aldehyde and/or the ketone as the other reactant is added during the course of the reaction and the aldehyde and/or the ketone is added in portions or continuously to the reaction mixture during the course of the reaction as a function of the achieved conversion of the nitrogen compound until a conversion of the nitrogen compound of at least 95% results, and all or part of the catalyst remains in the reaction vessel after the reaction batch and is reused for the next reaction batch.