Patent · US Active

Combination therapy for treating disease

US8038994B2 · kind B2 · utility

3Cited by
55References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 26, 2004
Grant dateOct 18, 2011
Priority date
Expiry dateMar 14, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/505
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are methods for treating cancer comprising administering a xenotypic antibody and a chemotherapeutic drug to a patient suffering from cancer. Also disclosed is a method for inducing a host immune response in a patient against a multi-epitopic in vivo tumor antigen present in the host serum, which antigen does not elicit an effective host immune response, comprising administering to the patient a chemotherapeutic drug and a composition comprising a binding agent that specifically binds to a first epitope on the antigen and allowing the binding agent to form a binding agent/antigen pair, wherein an effective host immune response is elicited against a second epitope on the antigen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.